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Substance education

Amphetamine.

Misusing prescription or illicit stimulants can cause serious heart and nervous-system effects.

Also known as Adderall, Speed, Uppers. A name does not verify contents.

What it is

Amphetamine medicines have legitimate prescribed uses. Recreational use, taking someone else’s medicine or exceeding a prescription changes the risk.

Sources & review notes
  1. Amphetamine
    NIH / MedlinePlus · Accessed 2026-09-26 · Warnings, precautions and overdose
  2. Substance use — amphetamines
    NIH / MedlinePlus · Accessed 2026-09-26 · Health effects and dependence

Major risks

Misuse may cause agitation, high blood pressure, irregular heartbeat, seizures and serious heart problems. Existing heart disease is an important prescribing concern.

Sources & review notes
  1. Amphetamine
    NIH / MedlinePlus · Accessed 2026-09-26 · Warnings, precautions and overdose
  2. Substance use — amphetamines
    NIH / MedlinePlus · Accessed 2026-09-26 · Health effects and dependence

Dependence & withdrawal

Amphetamine can be habit-forming. Stopping after overuse can cause profound fatigue or depression. Discuss a treatment plan with a clinician.

Sources & review notes
  1. Amphetamine
    NIH / MedlinePlus · Accessed 2026-09-26 · Warnings, precautions and overdose

Medication review

MAOI and other medication interactions require a pharmacist or prescriber. Share all medicines and supplements; this page cannot clear a combination for you.

Sources & review notes
  1. Amphetamine
    NIH / MedlinePlus · Accessed 2026-09-26 · Warnings, precautions and overdose

Warning signs

Seizure, collapse, inability to wake or breathing difficulty requires 911. A fast or irregular heart rhythm with severe symptoms needs urgent assessment.

Sources & review notes
  1. Amphetamine
    NIH / MedlinePlus · Accessed 2026-09-26 · Warnings, precautions and overdose
  2. Substance use — amphetamines
    NIH / MedlinePlus · Accessed 2026-09-26 · Health effects and dependence

Interaction records

No published pair records are available for this substance. Missing information does not mean a combination is safe.

Open the interaction checker →

This resource provides general education, not medical advice or personal clearance to use a substance. No drug or combination is risk-free. For an emergency, call 911.