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Community care

Naloxone.

A medicine that can temporarily reverse opioid overdose. Emergency care is still essential.

Also known as Narcan. A name does not verify contents.

What it can and cannot do

Naloxone blocks opioid effects and can restore breathing after opioid overdose. It does not reverse every cause of unconsciousness or poisoning. If opioid exposure is possible, uncertainty should not stop its use.

Sources & review notes
  1. Access to Naloxone Can Save a Life During an Opioid Overdose
    FDA · Accessed 2026-09-26 · Temporary reversal, emergency response, OTC access

Give it and call 911

Use the specific product’s instructions. A further dose may be needed after 2–3 minutes if normal breathing has not returned. Follow the dispatcher’s directions for CPR or breathing support. Stay with the person.

Sources & review notes
  1. 5 Things to Know About Naloxone
    CDC · Published/updated 2024-05-02 · Accessed 2026-09-26 · Recognition, response, repeat doses and access
  2. Drug use first aid
    NIH / MedlinePlus · Published/updated 2026-04-13 · Accessed 2026-09-26 · First aid and emergency assessment

After someone wakes

Naloxone can wear off before the opioid. Dangerous symptoms may return, so the person still needs emergency care. Continue watching breathing until responders arrive.

Sources & review notes
  1. Access to Naloxone Can Save a Life During an Opioid Overdose
    FDA · Accessed 2026-09-26 · Temporary reversal, emergency response, OTC access

Where to get it

Some nasal-spray naloxone products are available without prescription. Ask a pharmacy or local health department about availability and low-cost community programs. Read the instructions before an emergency.

Sources & review notes
  1. 5 Things to Know About Naloxone
    CDC · Published/updated 2024-05-02 · Accessed 2026-09-26 · Recognition, response, repeat doses and access
  2. Access to Naloxone Can Save a Life During an Opioid Overdose
    FDA · Accessed 2026-09-26 · Temporary reversal, emergency response, OTC access

This resource provides general education, not medical advice or personal clearance to use a substance. No drug or combination is risk-free. For an emergency, call 911.