Substance education
Dextromethorphan (DXM).
Cough-medicine misuse can cause poisoning, including from other ingredients.
Also known as DXM, Robitussin, Robo. A name does not verify contents.
What it is
DXM is a cough suppressant in many over-the-counter products. Misuse can cause dissociation, hallucinations, agitation and poor coordination.
Sources & review notes
- Dextromethorphan abuse: When to seek help
National Capital Poison Center · Accessed 2026-09-26 · Poisoning and combination products
Major risks
Poisoning can involve slowed breathing, seizures, coma and cardiovascular effects. Combination products may contain acetaminophen or other drugs with separate toxicities.
Sources & review notes
- Dextromethorphan abuse: When to seek help
National Capital Poison Center · Accessed 2026-09-26 · Poisoning and combination products
Serotonergic medicines
DXM can contribute to serotonin toxicity, including dangerous interactions with MAOI antidepressants. Other serotonergic medicines also need professional review.
Sources & review notes
- What is Serotonin Syndrome?
National Capital Poison Center · Accessed 2026-09-26 · Serotonergic medicines and clinical evaluation - Serotonin syndrome
NIH / MedlinePlus · Accessed 2026-09-26 · Medication interactions and symptoms
Repeated misuse
Ongoing misuse can disturb sleep and mood. Keep the product packaging for medical staff: DXM may not be the only ingredient involved.
Sources & review notes
- Dextromethorphan abuse: When to seek help
National Capital Poison Center · Accessed 2026-09-26 · Poisoning and combination products
Warning signs
Call 911 for seizure, breathing problems or inability to wake. If too much cough medicine may have been taken without those signs, call Poison Control promptly.
Sources & review notes
- Dextromethorphan abuse: When to seek help
National Capital Poison Center · Accessed 2026-09-26 · Poisoning and combination products - First aid: Act fast!
National Capital Poison Center · Accessed 2026-09-26 · 911 criteria and Poison Control contact
Interaction records
No published pair records are available for this substance. Missing information does not mean a combination is safe.
This resource provides general education, not medical advice or personal clearance to use a substance. No drug or combination is risk-free. For an emergency, call 911.