Interaction checker.

Choose two substances to view a sourced interaction record. This is not a complete interaction database or personal medical advice.

Severe risk

Alcohol + Benzodiazepines

Both depress the nervous system; combined exposure can dangerously suppress breathing.

Primary concerns

Profound sedation and respiratory depression.

Emergency concerns

Slow breathing or inability to wake: call 911.

Last source review: 2026-09-26 · source checked

Sources & review notes

Boxed Warning updated for benzodiazepines
FDA · Published/updated 2020-09-23 · Accessed 2026-09-26 · Dependence, withdrawal, alcohol and opioids
Understanding the Dangers of Alcohol Overdose
NIH / NIAAA · Accessed 2026-09-26 · Signs, combinations, bystander response

Risk labels describe the cited record, not the safety of a person or a dose. Two-substance records cannot establish the effects of three or more substances. Unknown ingredients and health conditions can change risks.