Interaction checker.

Choose two substances to view a sourced interaction record. This is not a complete interaction database or personal medical advice.

Severe risk

Ketamine + Alcohol

The ketamine label warns that alcohol and other depressants can compound sedation.

Primary concerns

Respiratory depression, coma and death.

Emergency concerns

Call 911 for difficulty waking or abnormal breathing.

Last source review: 2026-09-26 · source checked

Sources & review notes

KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3

Risk labels describe the cited record, not the safety of a person or a dose. Two-substance records cannot establish the effects of three or more substances. Unknown ingredients and health conditions can change risks.