Substance education
Ketamine.
Dissociation, sedation and bladder injury; depressant combinations can suppress breathing.
Also known as K, Special K. A name does not verify contents.
What it is
Ketamine is an anesthetic used under medical supervision. It can profoundly alter awareness and cause sedation or confusion. Monitored treatment does not establish recreational safety.
Sources & review notes
- KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3
Acute & repeated-use risks
Blood pressure and heart rate can change. Respiratory depression is possible. Chronic misuse is associated with bladder and urinary symptoms, including pain and frequent urination.
Sources & review notes
- KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3
Depressant combinations
Ketamine with alcohol, benzodiazepines or opioid medicines can cause profound sedation, suppressed breathing, coma and death.
Sources & review notes
- KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3
Awareness & injury
Disconnection from surroundings may make noticing danger or communicating symptoms harder. Summon medical help when someone is difficult to rouse.
Sources & review notes
- KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3 - Drug use first aid
NIH / MedlinePlus · Published/updated 2026-04-13 · Accessed 2026-09-26 · First aid and emergency assessment
Warning signs
Inability to wake or abnormal breathing requires 911. Do not assume deep sedation is a harmless part of the experience.
Sources & review notes
- KETALAR prescribing information
FDA · Published/updated 2022 · Accessed 2026-09-26 · Warnings, adverse reactions and interactions 7.3 - First aid: Act fast!
National Capital Poison Center · Accessed 2026-09-26 · 911 criteria and Poison Control contact
Interaction records
This resource provides general education, not medical advice or personal clearance to use a substance. No drug or combination is risk-free. For an emergency, call 911.