Substance education
NBOMe compounds.
Confirmed cases show seizures, overheating and serious organ injury.
Also known as 25B-NBOMe, 25C-NBOMe, 25I-NBOMe. A name does not verify contents.
What they are
NBOMe describes a group of synthetic psychoactive compounds, not one interchangeable product. Several have been analytically confirmed in poisoning cases.
Sources & review notes
- Two cases of severe intoxication with 25B-NBOMe and 25C-NBOMe
Hospital Authority Toxicology Reference Laboratory / Clinical Toxicology · Published/updated 2014-06 · Accessed 2026-09-26 · Seizures, overheating and muscle injury - Severe clinical toxicity associated with analytically confirmed 25I-NBOMe
Newcastle University / Clinical Toxicology · Published/updated 2013-07 · Accessed 2026-09-26 · Seven confirmed cases
Severe toxicity
Reported harms include marked agitation, rapid heart rate, high blood pressure, overheating and seizures. Muscle breakdown and kidney injury have occurred.
Sources & review notes
- Two cases of severe intoxication with 25B-NBOMe and 25C-NBOMe
Hospital Authority Toxicology Reference Laboratory / Clinical Toxicology · Published/updated 2014-06 · Accessed 2026-09-26 · Seizures, overheating and muscle injury - Severe clinical toxicity associated with analytically confirmed 25I-NBOMe
Newcastle University / Clinical Toxicology · Published/updated 2013-07 · Accessed 2026-09-26 · Seven confirmed cases
Evidence limits
Case series show serious harm can occur but cannot measure its frequency or establish safe conditions. Long-term outcomes and many combinations remain poorly characterized.
Sources & review notes
- Two cases of severe intoxication with 25B-NBOMe and 25C-NBOMe
Hospital Authority Toxicology Reference Laboratory / Clinical Toxicology · Published/updated 2014-06 · Accessed 2026-09-26 · Seizures, overheating and muscle injury - Severe clinical toxicity associated with analytically confirmed 25I-NBOMe
Newcastle University / Clinical Toxicology · Published/updated 2013-07 · Accessed 2026-09-26 · Seven confirmed cases
More than a psychological effect
Do not assume a product described as a psychedelic has only psychological effects. Heat, muscle rigidity and seizures require emergency assessment.
Sources & review notes
- Two cases of severe intoxication with 25B-NBOMe and 25C-NBOMe
Hospital Authority Toxicology Reference Laboratory / Clinical Toxicology · Published/updated 2014-06 · Accessed 2026-09-26 · Seizures, overheating and muscle injury - Severe clinical toxicity associated with analytically confirmed 25I-NBOMe
Newcastle University / Clinical Toxicology · Published/updated 2013-07 · Accessed 2026-09-26 · Seven confirmed cases
Warning signs
Call 911 for seizure, collapse, severe overheating or abnormal breathing. Tell responders the reported product without assuming identity is certain.
Sources & review notes
- Two cases of severe intoxication with 25B-NBOMe and 25C-NBOMe
Hospital Authority Toxicology Reference Laboratory / Clinical Toxicology · Published/updated 2014-06 · Accessed 2026-09-26 · Seizures, overheating and muscle injury - First aid: Act fast!
National Capital Poison Center · Accessed 2026-09-26 · 911 criteria and Poison Control contact - Severe clinical toxicity associated with analytically confirmed 25I-NBOMe
Newcastle University / Clinical Toxicology · Published/updated 2013-07 · Accessed 2026-09-26 · Seven confirmed cases
Interaction records
No published pair records are available for this substance. Missing information does not mean a combination is safe.
This resource provides general education, not medical advice or personal clearance to use a substance. No drug or combination is risk-free. For an emergency, call 911.